Once a brilliant scientist, Andross tested his weapons in the heart of one of Corneria’s biggest cities. After many warnings from Corneria’s ruling council, he persisted and was eventually captured and exiled by General Pepper. Of course, this was by no means the end of Andross, who set up shop on Venom. Being the enterprising ape that he is, he somehow managed to enslave the population of Venom and pollute the planet and just do lots of generally wicked things. That done, he went on to destroy the original Star Fox team by killing its leader, James McCloud and then launched various assaults on his own home planet of Corneria. He also appears to have aspirations of controlling the whole galaxy of Lylat, and is just generally a bit of a megolomaniac. What's not to love?!

Ganondorf Dragmire, or Ganon, as he is later known, is the archetypal villain of the Zelda series. There have been others of course, the Nightmares, Vaati, Majora...but none of them have ever come close to touching Ganondorf in terms of wickedness, longetivity or interest.

Gamespot writes that he is 'Practically the Darth Vader of video games, Ganon is able to fly, throw big mean balls of energy, cast menacing looks, command vast legions of servile minions, and return time after time, even after defeat. If nothing else, he's a tenacious bastard, and Nintendo seems to think that gamers must love shutting him down again and again because he's been around to torment Link and Zelda for quite some time.'

True indeed. Ganon has plagued Hyrule for literally hundreds, if not thousands, of years. In OoT, he ruled Hyrule for 7 dark years, turning Hyrule from a thriving world into a place of death and decay. In Windwaker, it seems apparent that his actions caused the Goddesses to destroy Hyrule as we knew it, and turn it into a vast watery domain.

His defeat in OoT lead to his imprisonment in the Golden Realm, a prison he would break free of centuries later, in Zelda 3: A Link to the Past. Again and again he has faced Link, again and again he has suffered defeat. However, there appears to be no final way to defeat him...did he truly face death in WW, or is there a way for him to come back? Who can say? A closing comment, written by Zombiekilla2002 seems at these stage apt...

You gotta be pretty fucking evil when one of your driving desires is to brutally murder two kids.

Sitting in her giant glass jar on Planet Zebes, Mother Brain commanded the Space Pirates with the help of the dragon-like Ridley. When a mysterious, parasitic life form named the ‘Metroid’ was discovered by the Galactic Federation, Mother Brain immediately began plans to create a whole army of the creatures. Fearing the worst, the Federation sent Samus Aran, a bounty hunter, to Zebes in order to stop the evil brain’s plans. Unfortunately for Mother Brain, neither Kraid nor Ridley could stop Samus from entering her lair, and had to resort to using her weapon systems to protect herself. Samus eventually succeeded in defeating the brain, but the war was not over yet…

Some time after her first encounter with Samus, Mother Brain heard news that the Metroid population had been wiped out, except for one hatchling that Samus had given the Space Science Academy for research purposes. Wanting to recreate her Metroid army, she sent Ridley to steal the hatchling from the lab where it was being kept. However, Samus, unable to stop the Space Pirate commander, followed him back to Zebes and once again made her way through the traps and monsters to Mother Brain’s lair. This time though, Mother Brain had a new trick up her sleeve. Once her jar was destroyed, she transformed into a giant, one-eyed monster, with her characteristic brain sticking out of the head. Samus tried her best to tackle the beast, but Mother Brain was able to use a powerful laser on the bounty hunter, that brought her to near death. It seemed as though the brain was going to win this time.

Before Mother Brain could finish off her opponent however, the hatchling that Samus had rescued and given to the Academy - which was now a full-grown Metroid - swooped in, attached itself to Mother Brain’s head, and sucked away at her energy. While the brain-monster fell to the ground, the Metroid then attached itself to Samus and restored her energy and gave her a new Hyper Beam weapon. Sadly, Mother Brain was quick to recover and killed Samus’ parasitic saviour as fast as she could. She then found out that she was no match for Samus’ new ability, and was once again defeated by the heroic bounty hunter. ~ Firehawk

Much like his brother(?) Wario, Waluigi's origin is shrouded in mystery... As of now not much is really known about this character other than that he hates Luigi.... A lot! Waluigi's hatred seams to have something do to with Luigi's success in the video game business. He's extremely jealous of his nicer and much friendlier counterpart, and has for some reason waited all these years to claim revenge. Anyway, he seams to be very good at Tennis so maybe he can finally get his revenge by beating Luigi in a tournament... - Text taken from Nintendoland.com

Little is known of Wario, only that he first entered the public eye way back when Super Mario Land 2 was released for the Gameboy. In a memorable advertising campaign (see advert below) he encouraged the viewer to turn against Mario and to try and stop him from 'collecting the 6 Golden coins.' People didn't listen, but in Super Mario Land 3, subtitled Warioland, the player took control of Wario and helped him amass a fortune in order to buy his own castle or...birdhouse.

Several games later, and it's not entirely certain just exactly HOW evil Wario actually is...an extract from the Mario Party manual reads: ' Mario looked around and smiled... All his friends were there: Luigi, Peach, Toad, Yoshi - even Wario and Donkey Kong.' Evil incarnate? Probably not. Wario is little more than a thieving version of Mario.

A strange, frog-like creature the managed to take over the dream world Subcon (possibly to spread bad dreams and nightmares, since some of his underlings are said to do those kinds of things), and who could be defeated by vegetables for some weird reason. This weakness was shared through his minions, too, so when Mario and his friends decided to save Subcon from him, they had an easy time finding the right attack method. When they found the nasty frog after getting past his army of weird creatures, Wart immediately started spitting bubbles from his mouth at them, but they just hurled vegetables down his throat until he died. And then Mario discovered that it was just a dream.~Firehawk